New "Nature" article by Dr. Baker and co-authors

Message boards : Rosetta@home Science : New "Nature" article by Dr. Baker and co-authors

To post messages, you must log in.

AuthorMessage
Sean Kiely

Send message
Joined: 31 Jan 06
Posts: 64
Credit: 43,992
RAC: 0
Message 79294 - Posted: 23 Dec 2015, 19:20:36 UTC

There's a new article by Dr. Baker and co-authors at Nature magazine:

Rational design of α-helical tandem repeat proteins with closed architectures
ID: 79294 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile dcdc

Send message
Joined: 3 Nov 05
Posts: 1829
Credit: 115,748,962
RAC: 59,103
Message 79311 - Posted: 26 Dec 2015, 22:56:42 UTC

That's awesome. Did that work use R@H calculations or was it done in-house?

Also, will that paper appear here at some point?: http://www.bakerlab.org/biblio/

D
ID: 79311 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
krypton
Volunteer moderator
Project developer
Project scientist

Send message
Joined: 16 Nov 11
Posts: 108
Credit: 2,164,309
RAC: 0
Message 79313 - Posted: 27 Dec 2015, 10:03:35 UTC - in response to Message 79311.  

That's awesome. Did that work use R@H calculations or was it done in-house?

Also, will that paper appear here at some point?: http://www.bakerlab.org/biblio/

D


TJ had a bunch of jobs running here on BOINC for this project. We use structure prediction tools to validate the designs which is all done here at Rosetta@home!
ID: 79313 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
David Baker
Volunteer moderator
Project administrator
Project developer
Project scientist

Send message
Joined: 17 Sep 05
Posts: 705
Credit: 559,847
RAC: 0
Message 79420 - Posted: 18 Jan 2016, 5:42:28 UTC

Yes-Rosetta@home was essential for the design of novel proteins described in the Nature paper "Exploring the repeat protein universe using computational protein design". You can get the PDF from our website as usual. We wrote the beginning and end of the paper to be accessible to a broad audience so please do take a look! Thank you again for critical contributions to this project and all of the current work in the group!
ID: 79420 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
sgaboinc

Send message
Joined: 2 Apr 14
Posts: 282
Credit: 208,966
RAC: 0
Message 79423 - Posted: 19 Jan 2016, 17:36:48 UTC
Last modified: 19 Jan 2016, 17:40:04 UTC

congrats for the publication, & cheers to researchers / scientists for all that effort & the volunteer distributed computing involved :D
this is *really* science true to the human effort all of it, it is great that r@h advances the frontier of science by making it happen :)
ID: 79423 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote

Message boards : Rosetta@home Science : New "Nature" article by Dr. Baker and co-authors



©2024 University of Washington
https://www.bakerlab.org