Interesting starting point for attacking Coronavirus

Message boards : Rosetta@home Science : Interesting starting point for attacking Coronavirus

To post messages, you must log in.

Previous · 1 · 2 · 3 · 4 · 5 · 6 · Next

AuthorMessage
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98567 - Posted: 17 Aug 2020, 18:39:20 UTC

A community’s sewage could give early warning of COVID-19 outbreaks, Yale study finds. Here’s how

https://www.courant.com/coronavirus/hc-news-coronavirus-yale-sewage-prediction-20200527-lc5o7shm4bfpvkj5ohmj3pmnei-story.html
ID: 98567 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98624 - Posted: 23 Aug 2020, 1:54:10 UTC

ID: 98624 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98709 - Posted: 28 Aug 2020, 12:25:49 UTC

MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses

https://science.sciencemag.org/content/early/2020/08/26/science.abb3753
ID: 98709 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98726 - Posted: 1 Sep 2020, 3:36:04 UTC

Antiviral used to treat cat coronavirus also works against SARS-CoV-2: U of A researchers

https://www.folio.ca/antiviral-used-to-treat-cat-coronavirus-also-works-against-sars-cov-2-u-of-a-researchers/


Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

https://www.nature.com/articles/s41467-020-18096-2


DARE-19: Dapagliflozin could target key mechanisms activated in COVID-19

https://www.healio.com/news/endocrinology/20200822/dare19-dapagliflozin-could-target-key-mechanisms-activated-in-covid19?utm_source=selligent&utm_medium=email&utm_campaign=news&m_bt=435990753314
ID: 98726 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98754 - Posted: 5 Sep 2020, 13:30:47 UTC

ID: 98754 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98816 - Posted: 7 Sep 2020, 22:16:30 UTC

ID: 98816 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98919 - Posted: 9 Sep 2020, 3:45:01 UTC

AstraZeneca Covid-19 vaccine study put on hold due to suspected adverse reaction in participant in the U.K.

https://www.statnews.com/2020/09/08/astrazeneca-covid-19-vaccine-study-put-on-hold-due-to-suspected-adverse-reaction-in-participant-in-the-u-k/
ID: 98919 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98946 - Posted: 10 Sep 2020, 20:53:08 UTC

Scientists chart weak spots in coronavirus protein that antiviral drugs can target

https://www.geekwire.com/2020/scientists-chart-weak-spots-coronavirus-protein-structure-antiviral-drugs-can-target/


De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

https://science.sciencemag.org/content/early/2020/09/08/science.abd9909


This one is from the University of Washington, and therefore probably involves Rosetta@home.

Designed antiviral proteins inhibit SARS-CoV-2 in the lab

https://newsroom.uw.edu/news/designed-antiviral-proteins-inhibit-sars-cov-2-lab
ID: 98946 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Jim1348

Send message
Joined: 19 Jan 06
Posts: 881
Credit: 52,257,545
RAC: 0
Message 98951 - Posted: 10 Sep 2020, 22:27:25 UTC - in response to Message 98946.  
Last modified: 10 Sep 2020, 22:29:07 UTC

This one is from the University of Washington, and therefore probably involves Rosetta@home.

Designed antiviral proteins inhibit SARS-CoV-2 in the lab

https://newsroom.uw.edu/news/designed-antiviral-proteins-inhibit-sars-cov-2-lab

Yes, it cites the same paper in Science as the one cited in the paper cited in this post:
https://boinc.bakerlab.org/rosetta/forum_thread.php?id=14206
(Also cited in your post by the way.)

Very well done.
ID: 98951 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98973 - Posted: 11 Sep 2020, 23:21:42 UTC

A Supercomputer Analyzed Covid-19 — and an Interesting New Theory Has Emerged

https://elemental.medium.com/a-supercomputer-analyzed-covid-19-and-an-interesting-new-theory-has-emerged-31cb8eba9d63
ID: 98973 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98974 - Posted: 11 Sep 2020, 23:22:50 UTC
Last modified: 11 Sep 2020, 23:23:35 UTC

duplicate
ID: 98974 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 98981 - Posted: 12 Sep 2020, 23:47:49 UTC - in response to Message 98919.  

Coronavirus: Oxford University to resume vaccine trial after pause

https://www.bbc.com/news/uk-54132066
ID: 98981 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
ondrej.kubu@seznam.cz

Send message
Joined: 29 Nov 09
Posts: 2
Credit: 81,722
RAC: 0
Message 99095 - Posted: 22 Sep 2020, 20:15:33 UTC

Another site for potential treatment.

[url] https://science.sciencemag.org/content/early/2020/09/18/science.abd3255 [/url]
ID: 99095 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 99104 - Posted: 22 Sep 2020, 22:51:34 UTC - in response to Message 99095.  

Another site for potential treatment.

https://science.sciencemag.org/content/early/2020/09/18/science.abd3255

I made the link clickable.
ID: 99104 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 99121 - Posted: 25 Sep 2020, 12:49:35 UTC

Pulling the plug on COVID-19

https://sciencenode.org/feature/Pulling%20the%20plug%20on%20coronavirus.php?clicked=readmore


Some previous versions of the Rosetta@home application had the ability to check zinc binding with proteins. Does the current version still have this ability?

ECCVID 2020: Lower plasma zinc levels associated with increased risk of death in COVID-19 patients

https://www.univadis.com/viewarticle/eccvid-2020-lower-plasma-zinc-levels-associated-with-increased-risk-of-death-in-covid-19-patients-099310b9-68de-323e-940f-17b5d9e56b47


The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365891/
ID: 99121 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 99154 - Posted: 26 Sep 2020, 22:43:54 UTC

Simple blood test predicts patients most likely to die from COVID-19

https://newatlas.com/health-wellbeing/coronavirus-blood-test-predicts-mortality-disease-severity-rdw/
ID: 99154 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 99249 - Posted: 6 Oct 2020, 3:03:42 UTC

An Antioxidant Enzyme [url]Therapeutic for COVID‐19

https://onlinelibrary.wiley.com/doi/10.1002/adma.202004901
ID: 99249 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Jim1348

Send message
Joined: 19 Jan 06
Posts: 881
Credit: 52,257,545
RAC: 0
Message 99251 - Posted: 6 Oct 2020, 19:26:20 UTC - in response to Message 99249.  

An Antioxidant Enzyme [url]Therapeutic for COVID‐19

That seems to be an all-in-one solution. I hope it works out.
ID: 99251 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 99259 - Posted: 8 Oct 2020, 0:32:39 UTC

ID: 99259 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile robertmiles

Send message
Joined: 16 Jun 08
Posts: 1225
Credit: 13,875,446
RAC: 3,002
Message 99318 - Posted: 12 Oct 2020, 1:23:26 UTC

SARS-CoV-2 infection can block pain, opening up unexpected new possibilities for research into pain relief medication

https://theconversation.com/sars-cov-2-infection-can-block-pain-opening-up-unexpected-new-possibilities-for-research-into-pain-relief-medication-146280
ID: 99318 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Previous · 1 · 2 · 3 · 4 · 5 · 6 · Next

Message boards : Rosetta@home Science : Interesting starting point for attacking Coronavirus



©2024 University of Washington
https://www.bakerlab.org