What is Rosetta@home?
Play the FoldIt interactive game!

Rosetta@home needs your help to determine the 3-dimensional shapes of proteins in research that may ultimately lead to finding cures for some major human diseases. By running the Rosetta program on your computer while you don't need it you will help us speed up and extend our research in ways we couldn't possibly attempt without your help. You will also be helping our efforts at designing new proteins to fight diseases such as HIV, Malaria, Cancer, and Alzheimer's (See our Disease Related Research for more information). Please join us in our efforts! Rosetta@home is not for profit.
Follow us on Twitter: @rosettaathome        

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Join Rosetta@home
  1. Rules and policies
  2. System requirements
  3. Download, install, and run BOINC
    (enter the project URL:
  4. A welcome from David Baker
  5. Donate
Returning participants

User of the day                

r0n1 Profile
  Server Status as of 19 Apr 2014 19:31:44 UTC  
[ Scheduler running ]
Total queued jobs: 5,656
In progress: 439,553
Successes last 24h: 208,796
Users (last day ) :
376,432 (+31)
Hosts (last day ) :
1,215,750 (+205)
Credits last 24h :
Total credits :
TeraFLOPS estimate: 134.908

Apr 19, 2014
Predictor of the day: Congratulations to trever (Team Picard) for predicting the lowest energy structure for workunit gr040414_ama1_longee_newhair1184_fold_SAVE_ALL_OUT_157612_0 !

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Apr 2, 2014
Journal post from David Baker

There has been very exciting recent progress in designing vaccines and small molecule binding proteins using Rosetta that is described in two recent papers in Nature. These and other recent advances are described in the new Rosetta@Home Research Updates thread. It was suggested there that we send out a monthly email newsletter describing recent progress--we haven't done this before to avoid clogging everybody's inboxes but we certainly could if there is interest.

Feb 5, 2014
UPDATE - We successfully moved all the hardware that supports Rosetta@Home to new a home, some 25 m from it's old location. We did this to help balance the heat load in the datacenter as well as gain more physical space and electrical power for future R@H expansion (if we can afford it). -KEL and DOVA

Nov 10, 2013
Journal post from David Baker

An article mentioning Rosetta@Home recently appeared in the Globe and Mail:

Oct 10, 2013
The minirosetta application has been updated to 3.48. Please report bugs in this thread

Sep 25, 2013
Journal post from David Baker

Our new Institute for Protein Design is making considerable progress as you can see at we are now using Rosetta@home to rigorously evaluate all computer-based designs before we create synthetic genes to make the proteins in the laboratory. this is dramatically increasing our success rate at designing proteins with new functions. your contributions continue to be absolutely invaluable!


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Last Modified: 23 May 2013 17:26:37 UTC
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