Posts by Malcolm Cole

1) Message boards : Rosetta@home Science : Understanding project tags (Message 47904) Posted 22 Oct 2007 by Malcolm Cole Post: I was wondering if anyone could give me a short explaination as to how I might identify what kind of proteins and structures my computer has been working on? I am new to the site and project, but have been running my computer basically nonstop on boinc to help the cause. Thanks for the time in advance. Rosetta gave me a way of helping Science investigate proteins. I originally just hoped that the work would one day lead to a cure for Multiple Myeloma, probably too late for me, but it would help others. After a year of so, I am gradually assimilating some of the knowledge included in these posts, home pages and published articles. I can see now that protein folding has wider ramifications than my own need, but all the various aims would appear to inter-react. Drawing different scientific specialities together will inevitably help to trigger fresh ideas to the overall good of Rosetta. So I am delighted to let Rosetta download any work units for which it considers my computer suitable. My sincere thanks to every person running Rosetta, for I know some of your work units will be leading towards a cure for my cancer.
2) Message boards : Rosetta@home Science : 10 reasons I crunch R@H and you should too (Message 47846) Posted 19 Oct 2007 by Malcolm Cole Post: If you want 15 kids, you had better start figuring out how they can feed themselves and where they can live on this already overcrowded planet. There are too many of us already. Please forgive me if you think I am interferring, but I think I have done my bit, restricting my family to one fanastic young lady, who is now the architect of our experimental earth sheltered house. I think he was saying he's himself 15 years old today, not that he wants 15 kids. Heh. Whoops! I think you are right. Appologies to all concerned.
3) Message boards : Rosetta@home Science : 10 reasons I crunch R@H and you should too (Message 47801) Posted 17 Oct 2007 by Malcolm Cole Post: If you want 15 kids, you had better start figuring out how they can feed themselves and where they can live on this already overcrowded planet. There are too many of us already. Please forgive me if you think I am interferring, but I think I have done my bit, restricting my family to one fanastic young lady, who is now the architect of our experimental earth sheltered house.
4) Message boards : Rosetta@home Science : hope for cures (Message 46504) Posted 18 Sep 2007 by Malcolm Cole Post: I should have been dead from Multiple Myeloma by 1996 according to original prognosis. The doctors kept me alive with chemos and transplants. Yes, they damage the body, but it recovers - so does the cancer and that has to be attacked again. Now I am on to Phase 1 trials as the only way to get at the latest very expensive partially directed drugs to help find out how they work. If I am very very lucky then the doctors will keep me alive long enough for these protein folding calculations to allow doctors to direct medication directly at the cancer cells, then we may have a cure for cancers in general. Horray for Rosetta, and all the staff and people who sail/fly with her!
5) Message boards : Rosetta@home Science : will the data be used for animal testing? (Message 45554) Posted 28 Aug 2007 by Malcolm Cole Post: No, the drug companies would leave the sector and concentrate on areas where already far too many are moving, i.e. into vanity drugs. Allowing rich old women to try and pass themselves off as young things. Come on, lets have a little less cynicism! We are all contributing our resources to a worthwhile cause, and most of the staff in the drug companies think they are contributing too. Without the drug companies I would already be dead. It is the manufacturers' trials that are keeping me alive. Well done everyone who is working to understand our chemistry and physics. There will be plenty more new jobs to be tackled, when current tasks are resolved, just as has always happened in the past.
6) Message boards : Rosetta@home Science : Prototype of Rosetta "game" (Message 45126) Posted 18 Aug 2007 by Malcolm Cole Post: Regret the X in the box does not activate for me either. I am using Microsoft Internet Explorer 7.0 and Java 6 Update 2, which I think are the latest in the UK. Is the game working with these versions anywhere else?