Yet another paper from the Baker lab - this time in Science!

I last posted about Yang Hsia's work designing an icosahedron from a single protein subunit that could be used to deliver drugs or to develop powerful new vaccines. In new work published last week, Baker lab scientists and collaborators have taken this work to an exciting new level by engineering 120-subunit icosahedral nanocages that self-assemble from not one, but two distinct protein components. The advantage of having two components is the ability to control assembly of the nanoparticle by mixing the individually prepared subunits.

The new designed proteins are described in the latest issue of Science in a paper entitled “Accurate design of megadalton-scale multi-component icosahedral protein complexes”.

Here is a link to the IPD news post about the work. It also contains links to other articles about this exciting work.

Science did a great profile on David Baker and protein design which you can read here.

Accompanying video on protein folding and design here!

So far as settings go, I'd just check to ensure you allow tasks to remain in memory while suspended. Windows will swap the memory used by suspended tasks out to disk for you, but it let's the task later pick up where it left off rather than losing work (and sometimes, perhaps reporting failures as it tries to get restarted).