Message boards : Rosetta@home Science : The real proteins in the WU's
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starhero21 Send message Joined: 31 May 15 Posts: 1 Credit: 1,616,329 RAC: 0 |
Is there any way to learn the actual names of the proteins that are sent to us for analysis? I just got a work unit with a protein that has a known native structure, and I want to learn more about it, and indirectly how the overall 3D structure determines properties. |
Murasaki Send message Joined: 20 Apr 06 Posts: 303 Credit: 511,418 RAC: 0 |
Some of the task names include references to the protein being studied. For example, your machine currently has task 738033377 with the description "5HTUBE_AB_5HTUBE_AB_043.pdb_15_06_00_14_41_globalDocking_2_SAVE_ALL_OUT_268540_42_0". Searching Google for 043.pdb brings up this entry from the protein data bank. I'm not an expert though so there may be other ways to identify a known protein your machine is workin on. |
Christopher Bahl Volunteer moderator Project developer Project scientist Send message Joined: 7 Feb 13 Posts: 9 Credit: 801,638 RAC: 0 |
Your "known native" is likely a de novo designed protein. This means it does not exist in the real world... yet. If a design passes the in silico folding test on Rosetta@home, we will likely attempt to produce it in the lab. Here's another thread that addresses a similar question: https://boinc.bakerlab.org/rosetta/forum_thread.php?id=6543&nowrap=true#77624 Cheers! -Chris |
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Rosetta@home Science :
The real proteins in the WU's
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