Decoded TREX

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Profile [VENETO] boboviz

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Message 73624 - Posted: 14 Aug 2012, 19:07:18 UTC

TREX

Professor Stuart Wilson, who led the groundbreaking project, said: "Protein production is an essential part of life for all organisms. This process involves reading the code in genes and converting this to a message which is ultimately decoded to make a protein.

"The message is made of a special molecule called mRNA. In all organisms from yeast through to man the mRNA is made in a compartment in the cell called the nucleus, but then has to be transported to a separate compartment, called the cytoplasm, where it is decoded to make a protein. This process of mRNA transport is essential for life and when it malfunctions in humans it can lead to diseases such as motor neuron disease or cancer."

Researchers have shown how proteins called TREX provide a mark on the mRNA which acts as the passport which unlocks a transporter protein called Nxf1, allowing it to land on the mRNA and transport it to the cytoplasm to create proteins.

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Message boards : Rosetta@home Science : Decoded TREX



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