I would like to set the number high to like 20,000 seconds or higher. But will it make the WU take longer or what. Also would more ram be better as the number gets higher? I currently have at least 1gb on the machine's I want to do this on. Thanks!

That sets the fastest interval that Rosetta is allowed to checkpoint to file. In essence, you'll be preventing Rosetta from saving its state such that tasks will start over from the beginning if Rosetta is restarted. It won't make the tasks take longer to complete or require it to use more RAM but you take a risk of losing crunching time if the application is interrupted.

Personally I leave this setting to something reasonable such as 5-10 minutes because the state saving takes a negligible amount of CPU time and brownouts here are not uncommon.

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