Hello,
I heard many things about casp7 on this site, the message boards and on other sites too, but I'm confused now. Is CASP7 only an application test, to test how accurent the computer predictions are, based on know structures or is rosetta+casp7 searching for unknown and new structures that aren't already known?

thanks

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CASP is a "blind test" performed every 2 years, where teams working on "protein prediction" from all over the world, submit their "predictions" (via computational methods) for target proteins (targets are the ones we see T301, T319, T320) which are currently being solved EXPERIMENTALLY (in the lab, via Xray crystallography).

So the target proteins structures of CASP7 are still unknown, but will become known in a few weeks / months.

One of the CASP7 targets T294 Xray structure was published early ("the exam question was leaked" so to say), so it was cancelled and they won't take mathematical predictions for it.

E-Mail from CASP team 16/06/2006

Bad news first ...
It was brought to our attention that a paper was published on CASP7
structure T0294 ( http://dx.doi.org/10.1016/j.jmb.2006.05.018 ).
As this happened less than 3 weeks after the target release, we are
canceling this target according to our rules. No models will be assessed
on this target. This information leak is not a fault of the SG center
that provided the target, as the publication is from another group that
solved the same protein.

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