Rosetta's role in fighting coronavirus

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Message 92971 - Posted: 1 Apr 2020, 19:13:33 UTC - in response to Message 92970.  

Can we please follow the forum rules and focus the discussion on COVID-19 related research? I've been spending too much time away from more important duties for COVID-19 research having to monitor this thread.

I may have to lock this thread if it persists.
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The red spirit
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Message 93116 - Posted: 2 Apr 2020, 22:09:34 UTC

Does anyone know what "Junior HalfRoid vs COVID-19" in project name mean? I'm only getting WU names like that and it made me a little bit curious. Also one file mentions database and methyl.
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Message 93150 - Posted: 3 Apr 2020, 3:15:00 UTC - in response to Message 93116.  

These are Brian's scaffold designs for COVID-19. The database is the rosetta database and includes N-methylated amino acid rotamer libraries for designing cyclic peptides which can be therapeutics.
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Message 93252 - Posted: 3 Apr 2020, 17:08:55 UTC - in response to Message 92237.  

...long list of target proteins we're interested in for COVID-19 (some of which are COVID-19 itself).

I'm so confused. No idea what proteins you're talking. Would love to hear more details.
Covid-19 is the disease.
SARS-CoV-2 is the virus.
NSP1, NSP2, NSP3, NSP4, NSP5, NSP6, NSP7, NSP8, NSP9, NSP10, NSP12 NSP13, NSP14, NSP15 ,NSP16, S, ORF3a, E, M, ORF6, ORF7a, ORF8, N & ORF10 are the proteins.
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Sam

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Message 93330 - Posted: 4 Apr 2020, 1:22:42 UTC

Suspended most of my other projects for now when I heard about Rosetta doing work for the virus.

Tried to run the Folding app but seemed to not like my system too much.

Glad I can do something small for it.

Greetings from Queens, NY. Stay safe everyone.
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Robert H

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Message 93383 - Posted: 4 Apr 2020, 14:41:09 UTC - in response to Message 93330.  

Suspended most of my other projects for now when I heard about Rosetta doing work for the virus.

Tried to run the Folding app but seemed to not like my system too much.

Glad I can do something small for it.

Greetings from Queens, NY. Stay safe everyone.


Good! Spread the word so more people can join the fight against the virus with their PC!
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Daniel

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Message 93556 - Posted: 5 Apr 2020, 21:09:12 UTC

My Android pixel 2xl is an arm64 device but it's not getting any Wu's. Something else I need to do?
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Message 93570 - Posted: 5 Apr 2020, 22:16:46 UTC

I'm happy to see more WU coming through, with 5/8 labeled as COVID 19!
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Message 93597 - Posted: 6 Apr 2020, 3:25:41 UTC - in response to Message 93570.  

Just discovered that Rosetta@Home is helping out in this fight. Redirecting the entire fleet, as it were, to both Rosetta and Ralph now.

Asking my somewhat long-lost team members at Team-SciFi to also do the same.

Anyone need a team to crunch this for...? ;)

look for Team-SciFi over at Rosetta if so...

<end shameless plug>

Phoenix


The Liver is EVIL. It must be PUNISHED!

Team-SciFi
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Message 93598 - Posted: 6 Apr 2020, 3:41:33 UTC

For people running older MacOS machines that were not able to crunch 4.12 tasks (Covid ones).. They just released 4.15 and it appears to be running fine on older hardware again. Thanks to the Dev's for figuring out the problem.
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Message 93670 - Posted: 6 Apr 2020, 19:39:21 UTC

Yup, if you want to use your GPU, Folding is a perfect choice.
Unluckily not every problem can be efficiently run on a GPU.
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Message 93686 - Posted: 6 Apr 2020, 22:22:21 UTC - in response to Message 91772.  

Sorry but need to ask serious question.

Should we now also be worried about hantavirus as cases in china popping up.

Also should this be looked into.

Hope not because incubation period is 8 weeks and symtoms to COVID-19 similar.
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Message 93703 - Posted: 7 Apr 2020, 2:10:22 UTC

Very proud to be able to contribute in the fight against COVID-19.
I will do my best to support this project.
Infinite thanks to all human beings who are fighting this Pandemic on all fronts.

Thanks Rosetta@home.
For a Better World!
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Message 93708 - Posted: 7 Apr 2020, 4:47:37 UTC - in response to Message 93686.  

Should we now also be worried about hantavirus as cases in china popping up.

The hantavirus is endemic to the Southwest U.S.
It is spread by rodents, and new cases pop up every few years.

I doubt it is a major problem just because there are a few cases in China, but you never know.
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Message 94103 - Posted: 10 Apr 2020, 20:18:43 UTC

Dear all,

I‘ve got a question popping up in the back of my head, and I hope, you won‘t get me wrong.
As we‘re all enthusiastic to offer capacity, I think, we‘re all doing this with the intention to help worldwide in this case.
I‘m from Germany, and please excuse if I‘ll hurt someones feelings, but all of what I‘ve learned in my life so far prevents me from trusting Donald Trump in the slightest.
The servers for which we‘re currently working are located in the US, is that correct?
Is there something like a proof, that our contribution will be used to help ALL COUNTRIES, regardless of Trump‘s „America first“ promises?
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Message 94104 - Posted: 10 Apr 2020, 20:21:35 UTC - in response to Message 94103.  
Last modified: 10 Apr 2020, 20:21:53 UTC

Dear all,

I‘ve got a question popping up in the back of my head, and I hope, you won‘t get me wrong.
As we‘re all enthusiastic to offer capacity, I think, we‘re all doing this with the intention to help worldwide in this case.
I‘m from Germany, and please excuse if I‘ll hurt someones feelings, but all of what I‘ve learned in my life so far prevents me from trusting Donald Trump in the slightest.
The servers for which we‘re currently working are located in the US, is that correct?
Is there something like a proof, that our contribution will be used to help ALL COUNTRIES, regardless of Trump‘s „America first“ promises?


This project was around long before Trump was president, and it will continue to be around long after he's gone.
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Profile Roland Gericke

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Message 94105 - Posted: 10 Apr 2020, 20:29:32 UTC - in response to Message 94104.  

I really hope so, but as long as he has the power, my question concerns me.
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Jim1348

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Message 94107 - Posted: 10 Apr 2020, 20:32:41 UTC - in response to Message 94105.  

I really hope so, but as long as he has the power, my question concerns me.

Most people here would leave if they thought Donald had anything to do with it.
But do what you want. There are plenty of others.
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Millenium

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Message 94109 - Posted: 10 Apr 2020, 20:52:59 UTC

Indeed as an European, partecipating to a project in the epoch of "america first" is indeed concerning.
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Message 94110 - Posted: 10 Apr 2020, 21:11:50 UTC - in response to Message 94109.  
Last modified: 10 Apr 2020, 21:24:36 UTC

This is at a university. Any commercial application of the information developed here is down the road.
You can get concerned at some point I suppose, but this is much too basic a level for that.

EDIT: European companies can use the information developed here too of course. Getting them interested enough to spend the money on development will probably be the biggest hangup.
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Message boards : News : Rosetta's role in fighting coronavirus



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