Rosetta's role in fighting coronavirus

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Message 92453 - Posted: 28 Mar 2020, 13:50:56 UTC - in response to Message 92420.  
Last modified: 28 Mar 2020, 20:03:26 UTC


Have to ask as a noob, though - what is the max ideal turnaround time for a slow PC? The laptops I'm running WUs on can take 10-12 hours per WU - and I can abort the Rosetta queue so I'm not slowing the research down.


I think they are all supposed to take around 8 hours (of cpu time) no matter how fast or slow the machine. They must be scaling the wus based on benchmarks.


To clarify - I asked about turnaround time (the time between downloading the WU and submitting it for validation) - as the project team member was talking about. They said they were more concerned about turnaround time, not CPU time. Thanks for trying to help, though!


The time per WU is based on a user preference for preferred runtime. Each machine, regardless of how fast it runs, tries to get as much done within that runtime preference as possible. Keep in mind that the preference refers to actual CPU time, not the "wall-clock" time (see the properties of a specific WU, where both times are shown).

All of the results are used. Regardless of how soon they were returned. I think they were simply saying that you don't need to babysit the machines. Try to set them up to get results returned within 48 hours if that is possible for your situation. You do this by reviewing your network preferences, and letting the machine run for a consistent number of hours per day, so the BOINC Manager can calibrate how much work to request to fill a cache of x.x days requested in the network preferences.
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Message 92472 - Posted: 28 Mar 2020, 17:03:22 UTC - in response to Message 92064.  

thats true
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Message 92477 - Posted: 28 Mar 2020, 17:48:44 UTC - in response to Message 92148.  
Last modified: 28 Mar 2020, 17:50:14 UTC

I agree with james. Lets get some priorities straight over there in the Lab. Doubled CPU time in the last short period... that is only for one reason, Covid19. Someone needs to do some rescheduling.
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Laurent

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Message 92487 - Posted: 28 Mar 2020, 20:20:35 UTC - in response to Message 92477.  

Let's be honest:

Best case they find something where the drug already exists. In that case, it will take at least one month (usually more) to come from the in-silico result to a WHO guideline and general availability of the drug. Most countries are way past that window of opportunity and will go though the first wave of infections w/o such a drug.

Second best case: they find something that can be used to create a drug. Even using an emergency protocol (direct testing on humans), it will be at least 3 months, more likely 6 months before the general population has got that shot.

This box of pandora is wide open and even knowing this, some countries still treat it like a seasonal flu. Germany currently expects roughly 70% of the population to get infected till the end of the year (if we stay in current lockdown mode). Dead rate is somewhere between 1% and 5%, depending on who (or WHO) you trust. That's somewhere between 0.5mio and 2.8mio COVID-19 deaths in Germany. Now look at the US and ask yourself what will happen worldwide after COVID-19 has become endemic there.

The next few boxes of pandora are already waiting for us. We had one every few years (SARS, MERS, Ebola, ....). Those upcoming boxes might be even scarier, faster, deadlier. Example: mumps in adult males causes the sperm count to drop permanently (Anti-vaxer might take notes now). The effect is minor, usually not enough to make males infertile. Now assume a variant causes a bit more damage and in females. Can you image a world after something sweeping whole continents mostly uncontrolled / unnoticed because nobody has a test for that one?

Science is working on the next boxes of pandora and should hopefully be at least a few years before the curve. The corona-family was known beforehand, that's why we can test for infections, that's why we can track it (20-40% of the cases are asymptomatic). That's why switching to COVID-19 only mode is not a good idea even if it keeps some users around for longer.

Science needs time and resources. Swamping science with resources AFTER the fact doesn't work.
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Message 92492 - Posted: 28 Mar 2020, 21:44:44 UTC - in response to Message 92487.  
Last modified: 28 Mar 2020, 22:30:26 UTC

Science needs time and resources. Swamping science with resources AFTER the fact doesn't work.

Exactly so. This is long-range work. Masks and gloves are the short-range tools, along with social distancing.
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Message 92495 - Posted: 28 Mar 2020, 23:50:44 UTC - in response to Message 92453.  


Have to ask as a noob, though - what is the max ideal turnaround time for a slow PC? The laptops I'm running WUs on can take 10-12 hours per WU - and I can abort the Rosetta queue so I'm not slowing the research down.


I think they are all supposed to take around 8 hours (of cpu time) no matter how fast or slow the machine. They must be scaling the wus based on benchmarks.


To clarify - I asked about turnaround time (the time between downloading the WU and submitting it for validation) - as the project team member was talking about. They said they were more concerned about turnaround time, not CPU time. Thanks for trying to help, though!


The time per WU is based on a user preference for preferred runtime. Each machine, regardless of how fast it runs, tries to get as much done within that runtime preference as possible. Keep in mind that the preference refers to actual CPU time, not the "wall-clock" time (see the properties of a specific WU, where both times are shown).

All of the results are used. Regardless of how soon they were returned. I think they were simply saying that you don't need to babysit the machines. Try to set them up to get results returned within 48 hours if that is possible for your situation. You do this by reviewing your network preferences, and letting the machine run for a consistent number of hours per day, so the BOINC Manager can calibrate how much work to request to fill a cache of x.x days requested in the network preferences.


Thanks for replying - I'm currently running my devices as close to 24/7 as possible, due to the temporary elimination of time-of-use electricity rates in my area. I appreciate the help - I'll adjust my rosetta@home preferences accordingly.
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Message 92496 - Posted: 28 Mar 2020, 23:52:24 UTC
Last modified: 28 Mar 2020, 23:56:51 UTC

team Challenge
https://www.boincstats.com/stats/challenge/team/chat/1074
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Message 92498 - Posted: 29 Mar 2020, 2:08:53 UTC - in response to Message 92496.  

team Challenge
https://www.boincstats.com/stats/challenge/team/chat/1074


This is gonna be interesting - looking forward to it!
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Message 92499 - Posted: 29 Mar 2020, 3:06:15 UTC - in response to Message 92498.  

in 6 day's from now😁 it well become the worlds largest network super computer ever.
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Message 92503 - Posted: 29 Mar 2020, 5:05:34 UTC - in response to Message 92499.  

in 6 day's from now😁 it well become the worlds largest network super computer ever.

Lets hope so.
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Message 92568 - Posted: 29 Mar 2020, 23:14:23 UTC - in response to Message 92503.  

Just added my 384 threads after being gone for 2 years.... 11 servers 24/7. I don't care about the names. I'll run anything that comes down the network link... First units should be coming back in about 4 hours from the faster machines. Slowest machines are about 8 hours. All 1600 WUs downloaded should be back in about 24 to 28 hours
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Message 92570 - Posted: 29 Mar 2020, 23:47:57 UTC - in response to Message 92568.  

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Message 92574 - Posted: 30 Mar 2020, 1:12:00 UTC - in response to Message 92568.  

Just added my 384 threads after being gone for 2 years.... 11 servers 24/7. I don't care about the names. I'll run anything that comes down the network link...

Excellent. You may find that even with 32 GB of memory, the 12 core/24 thread machines might occasionally not be able to run all cores. I had that yesterday with my 6 core/12 thread machines with 16 GB, so I doubled it to 32 GB.
It is not a big deal, and not necessarily worth adding more memory, but you may see it with the new COVID-19s. The are almost 1.5 GB each.
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Message 92585 - Posted: 30 Mar 2020, 3:58:19 UTC - in response to Message 92496.  
Last modified: 30 Mar 2020, 3:59:22 UTC

team Challenge
https://www.boincstats.com/stats/challenge/team/chat/1074


Chances are very high that we're gonna finish last lol, but I just signed our tiny, but precious, team up!

If any of y'all are teamless, you're more than welcome to join!
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Message 92590 - Posted: 30 Mar 2020, 9:34:39 UTC - in response to Message 92568.  

Just added my 384 threads after being gone for 2 years.... 11 servers 24/7. I don't care about the names. I'll run anything that comes down the network link... First units should be coming back in about 4 hours from the faster machines. Slowest machines are about 8 hours. All 1600 WUs downloaded should be back in about 24 to 28 hours

That's awesome. Thank you for coming back!
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Message 92638 - Posted: 30 Mar 2020, 16:57:52 UTC - in response to Message 92590.  
Last modified: 30 Mar 2020, 16:58:26 UTC

My computer does not receive new jobs, maybe they are over. Waiting from China for i5-4690 instead of G1840.
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Message 92641 - Posted: 30 Mar 2020, 18:06:06 UTC - in response to Message 92638.  
Last modified: 30 Mar 2020, 18:06:35 UTC

My computer does not receive new jobs, maybe they are over. Waiting from China for i5-4690 instead of G1840.


According to the Server Status page, R@H is basically out of WU to send. Over 1.4 MILLION WUs out in the wild being crunched. I don't recall a time when there were so many WUs distributed out in this project.
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Message 92642 - Posted: 30 Mar 2020, 18:39:30 UTC - in response to Message 92641.  

According to the Server Status page, R@H is basically out of WU to send. Over 1.4 MILLION WUs out in the wild being crunched. I don't recall a time when there were so many WUs distributed out in this project.

Indeed!
On one side im so happy to see so much people joined, fighting togehter in the biggest war in the human history.
On the other side, Im very sad that we are joined for that reason.
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Message 92645 - Posted: 30 Mar 2020, 19:13:08 UTC - in response to Message 92574.  

I was draining down my 24 thread 32GB machines and had a mix of Rosetta and other work. 2 of the 3 machines were well into the swap file but I was to catch them before they ran out. Trimmed back some work and they are now working just fine. Once the other work drains off I will open them up again. The other machine was out of swap and totally thrashing (disk light on continuously and couldn't log on). Reboot and trimmed back some work like the others. On my 128 thread 256GB machine, it filled up the root filesystem as I only had 50GB allocated to it and when Rosetta started up with about 500MB per slot, BOINC died. I was able to still logon so was able to shrink some LVs and extend the root LV. All good now. Everything is running as expected.
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Message 92653 - Posted: 30 Mar 2020, 20:42:32 UTC - in response to Message 92642.  

According to the Server Status page, R@H is basically out of WU to send. Over 1.4 MILLION WUs out in the wild being crunched. I don't recall a time when there were so many WUs distributed out in this project.

Indeed!
On one side im so happy to see so much people joined, fighting togehter in the biggest war in the human history.
On the other side, Im very sad that we are joined for that reason.


As a newer user, I've never seen it under 15k in the last few days - here it is at just above 8k. It's great to see that we've come together - I just hope they stick around, so they can fight other diseases. Whether with Rosetta, or other projects.
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Message boards : News : Rosetta's role in fighting coronavirus



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