Rosetta@home has contributed to a number of recent publications. Congratulations and thank you!

Message boards : News : Rosetta@home has contributed to a number of recent publications. Congratulations and thank you!

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Message 87458 - Posted: 5 Oct 2017, 18:42:22 UTC
Last modified: 5 Oct 2017, 18:45:58 UTC

In Nature: building 20,000 new drug candidates. New de novo designed "mini-protein" binders were custom built to target either a deadly virus or a potent toxin and were shown to afford protection to mice. Read more.



Sensors for the potent opioid fentanyl. Using a fully-automated Rosetta design pipeline, high-affinity fentanyl sensors capable of detecting environmental fentanyl were produced. Read more.



In Science: data-driven protein design. This work achieves the long-standing goal of a tight feedback cycle between computation and experiment and has the potential to transform computational protein design into a data-driven science. Rather than observing thousands of complex natural proteins to try to deduce their folding rules, over 15,000 new, simpler proteins were built – all designed using Rosetta. Through multiple design rounds, features that led to successful folding were learned and incorporated into the design pipeline. Read more.


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Message 87460 - Posted: 6 Oct 2017, 9:53:11 UTC - in response to Message 87458.  

Well done!!
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Message boards : News : Rosetta@home has contributed to a number of recent publications. Congratulations and thank you!



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