Foldit important update

Message boards : Rosetta@home Science : Foldit important update

To post messages, you must log in.

AuthorMessage
Profile [VENETO] boboviz

Send message
Joined: 1 Dec 05
Posts: 1994
Credit: 9,633,537
RAC: 7,232
Message 102261 - Posted: 22 Jul 2021, 7:06:36 UTC

From Foldit site:
Hey everyone!

We've just pushed out an update with some big changes to our underlying biochemistry software, Rosetta.

Rosetta provides Foldit with algorithms that represent the state-of-the-art of protein biochemistry modeling. However, the version of Rosetta you are using is now quite a few years out of date, and we'd like to get back to the cutting edge.

This update brings us up-to-date with the latest version of Rosetta. You hopefully shouldn't actually notice any changes... yet. The benefits of this update will come down the road as we begin to take advantage of the features in this more capable version of Rosetta.

ID: 102261 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile [VENETO] boboviz

Send message
Joined: 1 Dec 05
Posts: 1994
Credit: 9,633,537
RAC: 7,232
Message 102330 - Posted: 2 Aug 2021, 6:48:00 UTC
Last modified: 2 Aug 2021, 6:48:16 UTC

Another important update to Foldit - implementation of AlphaFold:
Amazing new AI software is now at your fingertips, and you can use it to boost confidence in your own protein designs!


And video news
ID: 102330 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile [VENETO] boboviz

Send message
Joined: 1 Dec 05
Posts: 1994
Credit: 9,633,537
RAC: 7,232
Message 102337 - Posted: 4 Aug 2021, 7:43:37 UTC

Here more details
ID: 102337 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile [VENETO] boboviz

Send message
Joined: 1 Dec 05
Posts: 1994
Credit: 9,633,537
RAC: 7,232
Message 104667 - Posted: 5 Feb 2022, 15:06:06 UTC - in response to Message 102330.  

Another important update to Foldit - implementation of AlphaFold:


The "interface" with AlphaFold started the last summer like an experiment (they didn't know if it would have been useful or not).
Now they want to "expand" this possibility with a new tool: "Neural Net Tool"

What a exciting years for molecular design!!
ID: 104667 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Jim1348

Send message
Joined: 19 Jan 06
Posts: 881
Credit: 52,257,545
RAC: 0
Message 104668 - Posted: 5 Feb 2022, 15:40:53 UTC - in response to Message 104667.  

What a exciting years for molecular design!!

It seems that they are systematizing Foldit more and more. I have not tried it, but if success is predicted more and more by distrogram data, and if problem areas are addressed by trying out a large number of amino acids, does that not suggest that it could be done with computers rather than humans?
ID: 104668 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile [VENETO] boboviz

Send message
Joined: 1 Dec 05
Posts: 1994
Credit: 9,633,537
RAC: 7,232
Message 104669 - Posted: 5 Feb 2022, 18:51:31 UTC - in response to Message 104668.  

I have not tried it, but if success is predicted more and more by distrogram data, and if problem areas are addressed by trying out a large number of amino acids, does that not suggest that it could be done with computers rather than humans?


Up to now, no. Human "intuition" is still required.
But the union of AI + Human intelligence + Computational power are opening new pages of research
ID: 104669 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote
Profile [VENETO] boboviz

Send message
Joined: 1 Dec 05
Posts: 1994
Credit: 9,633,537
RAC: 7,232
Message 104839 - Posted: 16 Feb 2022, 13:57:38 UTC

Foldit new release:

We've just released an update with the following fixes and features:

General:
* The HBNet filter will now only show BUNS when the network is hovered over.
* Panels now are brought to the front when they are toggled visible.
* Move AlphaFold button from Main Menu to Action Bar.

Bug Fixes:
* Fixed an issue causing the game to spam empty directories to the filesystem.
* Fixed a number of issues with backbone pins being reset, or displaying incorrectly.
* Fix disulfide display in the Collagen Education Mode puzzle.
* Fix how we handle the close window button for Linux clients.
* Fix some crashes in scoring related to hydrogen bonds.
* Fixed a crash on puzzle loading.
* View Options should retain information from the options.txt on puzzle load
* Missing View Options like "Show Clashes" should appear as normal on tutorial puzzles

ID: 104839 · Rating: 0 · rate: Rate + / Rate - Report as offensive    Reply Quote

Message boards : Rosetta@home Science : Foldit important update



©2024 University of Washington
https://www.bakerlab.org