Posts by Ed and Harriet Griffith

1) Message boards : Rosetta@home Science : CASP 11? (Message 77761)
Posted 24 Dec 2014 by Profile Ed and Harriet Griffith
Post:
An update on the results of CASP 11 would be appreciated.


Casp11 Abstracts

Are you pleased with the results? any surprises? Is CASP still worth dong?
2) Message boards : Rosetta@home Science : CASP 11? (Message 77293)
Posted 6 Aug 2014 by Profile Ed and Harriet Griffith
Post:
Thanks for an excellent easily understandable description. I am curious about each CASP.
Just in case anyone is curious, CASP 11 is almost complete!

If you see any jobs with a prefix Tp/Tx/Tc/Ts these are the casp targets.

This year the CASP organizers decided to change things a little.

For each target amino acid sequence, there are 4+ stages, at each stage more and more information is provide. What the organizers are interested in determining is how much and what kind of information is needed before we can predict the structure accurately.

T0 = no information except the sequence is provided
Tp = predicted contacts are provided (typically most are incorrect)
Ts = sparse simulated NMR data is provided
Tx = Cross-link data is provided
Tc = Only the correct contacts from Tp are provided.

I can go into more detail about any one of these, if anyone is curious.

At this stage, for some of the targets, we know how far we are from the true or "native" answer, but we won't know how the other groups did in comparison till a few months from now.

3) Message boards : Rosetta@home Science : CASP 11? (Message 76467)
Posted 20 Feb 2014 by Profile Ed and Harriet Griffith
Post:
Hi Ed,

Yes, Rosetta will be participating at CASP11. We've been working on improving the protocol. I'll post more details coming closer to May.

-krypton


Thanks! For we geeky competitive types, this is like the Superbowl!
4) Message boards : Rosetta@home Science : CASP 11? (Message 76430)
Posted 14 Feb 2014 by Profile Ed and Harriet Griffith
Post:
http://predictioncenter.org/casp11/index.cgi

That link says May-August 2014.

Thanks! I was also wondering if Rosetta had any special goals or plans to participate.
5) Message boards : Rosetta@home Science : CASP 11? (Message 76428)
Posted 14 Feb 2014 by Profile Ed and Harriet Griffith
Post:
Any word on CASP 11? Will there be one in 2014 or have we progressed beyond that?
6) Message boards : Rosetta@home Science : DISCUSSION of Rosetta@home Journal (5) (Message 72916)
Posted 29 Apr 2012 by Profile Ed and Harriet Griffith
Post:
BOINC Synergy based in Australia but with members all over just voted to make Rosetta Project of the Month for May 2012! Hope that helps with CASP 10!
7) Message boards : Rosetta@home Science : CASP9 (Message 69440)
Posted 20 Jan 2011 by Profile Ed and Harriet Griffith
Post:
Thanks Rochester for a very interesting article on what the University of Michigan is accomplishing in protein folding!
8) Message boards : Rosetta@home Science : CASP9 (Message 65977)
Posted 5 May 2010 by Profile Ed and Harriet Griffith
Post:
The team BOINC Synergy has selected Rosetta to be its project of the month for May! I hope the extra computing helps with CASP.
9) Message boards : Number crunching : When will minirosetta be standard? (Message 59361)
Posted 5 Feb 2009 by Profile Ed and Harriet Griffith
Post:
I am also getting rosetta beta 5.98 in addition to minirosetta 1.54. I am just curious as to any guesstimates when the mini-version will become the main one.
10) Message boards : Number crunching : When will minirosetta be standard? (Message 59348)
Posted 5 Feb 2009 by Profile Ed and Harriet Griffith
Post:
When will minirosetta be standard? If it is a cleaner version and can do everything the standard versions of Rosetta can do, will it ever be the only one used?
11) Message boards : Rosetta@home Science : DISCUSSION of Rosetta@home Journal (3) (Message 53094)
Posted 16 May 2008 by Profile Ed and Harriet Griffith
Post:
Will CASP 8 be on mini 119 and regular research be on beta 596? (Just curious to know what I am crunching - I will crunch both.)
12) Message boards : Number crunching : Problems with Rosetta version 5.85 (or 5.86 for linux) (Message 49225)
Posted 29 Nov 2007 by Profile Ed and Harriet Griffith
Post:
When I try to connect I get, "11/29/2007 11:35:29 AM|rosetta@home|Message from server: Project encountered internal error: shared memory"
13) Message boards : Number crunching : Way to go Rosetta! (Message 32405)
Posted 10 Dec 2006 by Profile Ed and Harriet Griffith
Post:
Rosettta now has over 100,000 users from 190 countries and over a billion credits!
14) Message boards : Number crunching : Why is the deadline still one week? (Message 22319)
Posted 12 Aug 2006 by Profile Ed and Harriet Griffith
Post:
Why is the deadline still one week? I thought we would go to two weeks when CASP was over.
15) Message boards : Number crunching : David, how's it going with the CASP due? (Message 21283)
Posted 28 Jul 2006 by Profile Ed and Harriet Griffith
Post:
Since I saw the request I have done 100% Rosetta. Two weeks is a pretty reasonable request and I like BOINC flexibility to do things like that. I assume this Friday evening the need will have passed and I can resume regular BOINCing. If this is not the case, someone let me know.
16) Message boards : Cafe Rosetta : Philosophy of disease research with emphasis on diabetes (Message 10460)
Posted 4 Feb 2006 by Profile Ed and Harriet Griffith
Post:
We could argue until kingdom come, but your posts are inappropriate. (And yes, I do think you are dumping on type 2 diabetics.) Please go to another thread to argue about how evil type 2 diabetics are and why they deserve less funding. Once again, my thread was to suggest that Rosetta has the potential to help diabetics. All the posts except yours have been responsive to that. Please go elsewhere to post your views. You are free to start your own thread, but I resent that you have hijacked my topic. I will no longer subscribe to this topic.
17) Message boards : Cafe Rosetta : Philosophy of disease research with emphasis on diabetes (Message 10440)
Posted 4 Feb 2006 by Profile Ed and Harriet Griffith
Post:
Type 2 diabeticvs do not deserve to be dumped on. Not all type 2 diabetics are overweight and many people who are very overweight do not develop diabetes. I am sorry you feel guilty about having type 2 diabetes, but the fact is the stress of trying to work and raise a family appears to be a factor in many of the diabetics I know. That seems very benign compared to having multiple sex partners or sharing needles for injecting illegal drugs. Despite this, AIDS appears to get more publicity. Please stop dumping on type 2 diabetics. Your experience may be more unique than you believe and counseling may help.
Again, the thrust of my suggestion was to say an improved Rosetta may eventually help diabetics. Let us not do a flame war please. If you want to discuss how the victims of some diseases are better or worse than others then please start your own thread.
Ed Griffith
18) Message boards : Cafe Rosetta : Philosophy of disease research with emphasis on diabetes (Message 9978)
Posted 27 Jan 2006 by Profile Ed and Harriet Griffith
Post:
I certainly don't want to get in a war with AIDS funding, a legitimate activity. I also claim no high moral ground. I do, however, respectfully disagree that being overweight is in the same catagory as having multiple sex partners and using illegal drugs. I readily acknowledge that there are many innocent victims of AIDS. Being overweight is a factor, but not a cause, in diabetes. Stress is also a factor.
The thrust of my arguement is that diabetes is serious (Many who die from heart attacks have diabetes as a contributing factor.) and distributed computing can help.
Ed Griffith
19) Message boards : Cafe Rosetta : Philosophy of disease research with emphasis on diabetes (Message 9884)
Posted 26 Jan 2006 by Profile Ed and Harriet Griffith
Post:
Truly excellent responses to the potential for using Rosetta in diabetes research. AIDS gets a lot of attention, but to a large degree it is caused by lifestyle choices. Diabetes is a working person's disease which takes a heavier toll. My suggestion is just that you include diabetes under the "Disease Related Research" listing on the front page of Rosetta's home page. Thanks for your consideration.
20) Message boards : Cafe Rosetta : Why I love Rosetta (Message 8319)
Posted 4 Jan 2006 by Profile Ed and Harriet Griffith
Post:
-It gives the most credits.

Not to pick a fight, but based on CS per second; CPDN wins ...


Could be, I left CPDN awhile back for other reasons. All projects are good for the benefit of mankind, these are just some of the reasons Rosetta is currently my favorite.


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