Posts by Mel

1) Message boards : Number crunching : Minirosetta 1.90 and 1.91 (Message 62726) Posted 2 Aug 2009 by Mel Post: I can no longer run Rosetta as none of my 4 machines will load minirosetta-database-rev31588.zip. This all started on the 30th of July. I have been running Rosetta since 2006 and this is the first time for this problem, however, it will run using version 5-10-45 ONLY. Is there a fix for this or do I just have to run the old version ??????????????
2) Message boards : Number crunching : Minirosetta 1.90 and 1.91 (Message 62725) Posted 2 Aug 2009 by Mel Post: This version should solve the slowing down, and instant quitting problems. New protocol added for predictions of changes in protein stability by mutations. ----- DEK posted an explanation on what caused all the trouble in the last week: http://boinc.bakerlab.org/rosetta/forum_thread.php?id=5011&nowrap=true#62640 Here are some more details on what was done so far: 1. The signature problem that initially causes massive network traffic was solved on Monday. 2. The slowing down of the program was caused by two large changes in the code. One of the changes is to allow rosetta to model large, symmetric molecules (oligomers http://en.wikipedia.org/wiki/Oligomer). And the other is to allow modeling atomic interactions with higher definition. The bug introduced in the first change was fixed. And the second change is temporarily reversed until further evaluation of the computation cost. Now unfortunately, due to the signature error and the update of the program, the web server will be extremely busy for the next few days. So downloading/uploading errors are still expected.
3) Message boards : Number crunching : Problems with Minirosetta Version 1.64/1.65 (Message 60941) Posted 1 May 2009 by Mel Post: [quote]We've got a new minirosetta version, with some infrastructure changes and a new protocol for using experimental data from NMR. PlU please report any issues here [/quote} How come each upload had been taking in excess of 25 minutes this week, it usually has only taken 20 seconds per work unit ? Have been on this upload now for 45 minutes and only upoading 80 work units.
4) Message boards : Number crunching : Problems with Minirosetta Version 1.64/1.65 (Message 60940) Posted 1 May 2009 by Mel Post: We've got a new minirosetta version, with some infrastructure changes and a new protocol for using experimental data from NMR. Please report any issues here