Posts by Admin

21) Message boards : News : Archived news. (Message 111763)
Posted 31 Aug 2015 by Admin
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We are experiencing technical difficulties with our servers and are currently troubleshooting. We hope to have things back to normal soon. Sorry for any inconvenience.
22) Message boards : News : Archived news. (Message 111762)
Posted 15 Jun 2015 by Admin
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The minirosetta application has been updated to 3.59. To report bugs, go to <a href=https://boinc.bakerlab.org/rosetta/forum_thread.php?id=6652>this thread</a>.
23) Message boards : News : Archived news. (Message 111761)
Posted 24 Mar 2015 by Admin
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<a href=http://www.aaas.org/annual-meeting/2015/plenaries/post-evolutionary-biology-design-novel-protein-structures-functions-assemblies>Here is a video</a> of David Baker describing some of the research going on in the lab from his recent talk at the American Association for the Advancement of Science (AAAS) meeting. Note: you may have to scroll down a little to view the video.
24) Message boards : News : Archived news. (Message 111760)
Posted 9 Mar 2015 by Admin
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The minirosetta application has been updated to 3.54. To report bugs, go to <a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=6609>this thread</a>.
25) Message boards : News : Archived news. (Message 111759)
Posted 6 Jan 2015 by Admin
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Happy New Year to all! We just posted a brief synopsis of our CASP11 results in <a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=6574&nowrap=true#77808>this thread post</a>, and would like to say thank you for all your contributions! Thank you all!
26) Message boards : News : Archived news. (Message 111758)
Posted 15 Aug 2014 by Admin
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Here's an update from David Baker on the Institute for Protein Design's progress: <a href=http://www.ipd.uw.edu/letter-from-the-director-ipd-update/><b>Letter from the Director – IPD Update</b></a>
27) Message boards : News : Archived news. (Message 111757)
Posted 5 Aug 2014 by Admin
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<b>Slowdown Update:</b> As it turns out, the slow-down experienced during the last week of July was the result of a very large surge in users joining the project through a new campaign by <a href=http://charityengine.com>http://charityengine.com</a>. As the servers were behaving properly - just overwhelmed - and DK was on a well-deserved holiday, it was difficult for the rest of us to pin-point the cause. You can see the recent surge <a href=http://boincstats.com/en/charts/14/project/perDay/user/total/chart.png>here</a>. <br>We are looking at changing/expanding our webserver frontend to be more resilient to surges like this in the future. Yet again, we apologize for the frustration caused. -KEL
28) Message boards : News : Archived news. (Message 111756)
Posted 30 Jul 2014 by Admin
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We are aware of significant network slow-down between the subnet upon which our servers sit and the Internet beyond the UW campus. We are working with the UW's Network Operations team to pinpoint the cause. We apologize for the frustration caused. -KEL
29) Message boards : News : Archived news. (Message 111755)
Posted 20 Jun 2014 by Admin
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<a name=baker_journal_post_76855></a><b><a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#76855>Journal post</a> from David Baker</b><br><br>We have recently made great progress in designing self assembling materials from proteins and in designing proteins which selectively kill tumor cells. These efforts have benefited tremendously from Rosetta@Home! News releases on these advances are at <br />
<a href=http://hsnewsbeat.uw.edu/story/self-assembling-nanomachines-start-click> http://hsnewsbeat.uw.edu/story/self-assembling-nanomachines-start-click</a><br />
<a href=http://hsnewsbeat.uw.edu/story/computer-designed-protein-causes-cancer-cells%E2%80%99-death> http://hsnewsbeat.uw.edu/story/computer-designed-protein-causes-cancer-cells'-death</a><br />
30) Message boards : News : Archived news. (Message 111754)
Posted 28 May 2014 by Admin
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The minirosetta application has been updated to 3.52. This version includes a couple bug fixes for symmetric modeling. To report bugs, go to <a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=6444>this thread</a>.
31) Message boards : News : Archived news. (Message 111753)
Posted 29 Apr 2014 by Admin
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The minirosetta application has been updated to 3.50. For details and to report bugs, go to <a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=6427>this thread</a>.
32) Message boards : News : Archived news. (Message 111752)
Posted 2 Apr 2014 by Admin
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<a name=baker_journal_post_76576></a><b><a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#76576>Journal post</a> from David Baker</b><br><br>There has been very exciting recent progress in designing vaccines and small molecule binding proteins using Rosetta that is described in two recent papers in Nature. These and other recent advances are described in the new Rosetta@Home Research Updates thread. It was suggested there that we send out a monthly email newsletter describing recent progress--we haven't done this before to avoid clogging everybody's inboxes but we certainly could if there is interest.<br />
33) Message boards : News : Archived news. (Message 111751)
Posted 5 Feb 2014 by Admin
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UPDATE - We successfully moved all the hardware that supports Rosetta@Home to new a home, some 25 m from it's old location. We did this to help balance the heat load in the datacenter as well as gain more physical space and electrical power for future R@H expansion (if we can afford it). -KEL and DOVA
34) Message boards : News : Archived news. (Message 111750)
Posted 10 Nov 2013 by Admin
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<a name=baker_journal_post_76180></a><b><a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#76180>Journal post</a> from David Baker</b><br><br>An article mentioning Rosetta@Home recently appeared in the Globe and Mail:<br> <a href=http://www.theglobeandmail.com/news/national/meet-two-pioneers-of-immune-research/article15101089> http://www.theglobeandmail.com/news/national/meet-two-pioneers-of-immune-research/article15101089/</a>
35) Message boards : News : Archived news. (Message 111749)
Posted 10 Oct 2013 by Admin
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The minirosetta application has been updated to 3.48. Please report bugs in <a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=6307>this thread</a>
36) Message boards : News : Archived news. (Message 111748)
Posted 25 Sep 2013 by Admin
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<a name=baker_journal_post_76065></a><b><a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#76065>Journal post</a> from David Baker</b><br><br>Our new Institute for Protein Design is making considerable progress as you can see at http://ipd.uw.edu. we are now using Rosetta@home to rigorously evaluate all computer-based designs before we create synthetic genes to make the proteins in the laboratory. this is dramatically increasing our success rate at designing proteins with new functions. your contributions continue to be absolutely invaluable!<br />
37) Message boards : News : Archived news. (Message 111747)
Posted 20 May 2013 by Admin
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<a name=baker_journal_post_75630></a><b><a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#75630>Journal post</a> from David Baker</b><br><br>We have discovered how to make several new classes of protein structures! Rosetta@home has been absolutely critical in this work: when we design a sequence to fold into a new structure, the last thing we do before ordering a synthetic gene so we can make the protein in the laboratory is to send it out to you to predict the structure-if it folds to the structure we designed, we go ahead with it, but if you find that the lowest energy state is a different structure we go back to the drawing board. Our success rate in making brand new structures is far higher than I or anybody else ever expected, and the reason the success rate is so high is that your calculations provide a very stringent test of whether the designed sequence will actually fold the way it is supposed to. In the next few weeks I and other scientists here will describe to you the new classes of proteins we are making, and the many applications they will be useful for. Thank you for your absolutely essential contributions to this newly emerging scientific field!<br />
38) Message boards : News : Archived news. (Message 111746)
Posted 17 May 2013 by Admin
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We again experienced networking problems with the backend of the R@H system. We're up and running again, but the system will be sluggish as the backlogged tasks are worked through. -DOVA and KEL [Fri May 17 13:55:23 PDT 2013]</a>
39) Message boards : News : Archived news. (Message 111745)
Posted 26 Apr 2013 by Admin
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The minirosetta application is updated to 3.46. For details and to report bugs, go to <a href=http://boinc.bakerlab.org/rosetta/forum_thread.php?id=6222>this thread</a>
40) Message boards : News : Archived news. (Message 111744)
Posted 24 Apr 2013 by Admin
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The backend network to R@H became 'fussy' over the past week resulting in an overall slowdown in performance (related to the power outage?). The network was 'rebooted' and things are back to normal. -KEL and DOVA


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