BMAA, Alzheimer\'s, Parkinson\'s, and ALS

Message boards : Cafe Rosetta : BMAA, Alzheimer\'s, Parkinson\'s, and ALS

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Profile robertmiles

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Message 78552 - Posted: 7 Aug 2015, 0:59:49 UTC

A video related to research on BMAA and its possible relation to Alzheimer\'s, Parkinson\'s, and ALS:

Secrets to Alzheimer\'s, ALS and Parkinson\'s Disease: Dr. Paul Alan Cox at TEDxJacksonHole

http://tedxtalks.ted.com/video/Secrets-to-Alzheimers-ALS-and-P

Says that a dietary supplement called l-serine MIGHT be a suitable treatment for at least one of these. They are testing whether it is; not enough results yet to tell.


A web site that MAY offer a more detailed and more technical video (in English) on this:

http://www.ur.se/Produkter/170138-UR-Samtiden-Miljo-och-framtidstro-Klimatet-och-halsan

The instructions are in Swedish, though, so it\'s hard to tell if you can\'t read Swedish.
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Profile rochester new york
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Message 78568 - Posted: 11 Aug 2015, 17:18:40 UTC - in response to Message 78552.  
Last modified: 11 Aug 2015, 17:19:45 UTC

A video related to research on BMAA and its possible relation to Alzheimer\'s, Parkinson\'s, and ALS:

Secrets to Alzheimer\'s, ALS and Parkinson\'s Disease: Dr. Paul Alan Cox at TEDxJacksonHole

http://tedxtalks.ted.com/video/Secrets-to-Alzheimers-ALS-and-P

Says that a dietary supplement called l-serine MIGHT be a suitable treatment for at least one of these. They are testing whether it is; not enough results yet to tell.


A web site that MAY offer a more detailed and more technical video (in English) on this:

http://www.ur.se/Produkter/170138-UR-Samtiden-Miljo-och-framtidstro-Klimatet-och-halsan

The instructions are in Swedish, though, so it\'s hard to tell if you can\'t read Swedish.



http://www.ur.se/Produkter/170138-UR-Samtiden-Miljo-och-framtidstro-Klimatet-och-halsan
http://tedxtalks.ted.com/video/Secrets-to-Alzheimers-ALS-and-P
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Message 78968 - Posted: 22 Oct 2015, 4:34:04 UTC
Last modified: 22 Oct 2015, 4:47:25 UTC

A web site mentioning something that helps control the excess iron in the brain that occurs during Parkinson\'s disease:

2009-08-parkinson-disease-iron

It\'s an iron-binding protein, so adding iron to the metal ions your software can link to proteins might help investigate Parkinson\'s disease also.
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Message 79017 - Posted: 3 Nov 2015, 20:17:35 UTC

Do any fungi produce BMAA?

A new study connects Alzheimer\'s disease with a brain fungus
<http://www.dailykos.com/story/2015/10/27/1441252/-A-new-study-connects-Alzheimer-s-disease-with-a-brain-fungus>
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Message 80996 - Posted: 11 Jan 2017, 2:20:12 UTC
Last modified: 11 Jan 2017, 2:23:32 UTC

Most of the site is accessible only from within Sweden. However, I was able to access enough to use Google Translate to get this summary:

Paul Alan Cox, professor and director of the Institute for ethnomedicine in Wyoming, USA, shows one of the winners of the Earth\'s climate is getting warmer, namely the cyanobacteria. They like the heat, increasing in number and produce a neurotoxin called BMAA. This toxin is now suspected in turn cause including ALS and Alzheimer\'s disease in humans. Preferring Gets Title: Climate change, biodiversity and human health. Moderator: Henrik Ekman. Organizers: King Carl XVI Gustaf\'s 50th årsfond for Science, Technology and Environment, Royal. Agriculture and Forestry Academy, Royal Academy. Sciences, Engineering Sciences and the Confederation of Swedish Enterprise. From the arrangement Faith in the Future held in the Bernadotte Library at the Royal Palace March 22, 2012.


Some articles that seem relevant (some appear to be research papers, some written for the public):

Algae bloom toxin linked to Alzheimer\'s, other diseases
http://www.cbsnews.com/news/algae-bloom-toxin-linked-to-alzheimers-and-other-neurodegenerative-diseases/

Secrets to Alzheimer\'s, ALS and Parkinson\'s Disease: Dr. Paul Alan Cox at TEDxJacksonHole
https://www.youtube.com/watch?v=7jWi6WQQ9wo
You can skip the ad before the video.

New research offers hope for Alzheimer’s patients
http://www.jhnewsandguide.com/news/health/new-research-offers-hope-for-alzheimer-s-patients/article_ab9326a2-ddaf-53bf-84cd-9fe814f3fb19.html

The Emerging Science of BMAA: Do Cyanobacteria Contribute to Neurodegenerative Disease?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295368/

Dietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brain
http://rspb.royalsocietypublishing.org/content/283/1823/20152397

Research points to pond scum connection for ALS, Alzheimer’s diseases
http://www.mypalmbeachpost.com/lifestyles/health/research-points-pond-scum-connection-for-als-alzheimer-diseases/O23lvN1VdNFoxOBPGt86hI/

Could environmental toxins trigger amyloid plaques in the brain? An interview with Dr Paul Alan Cox
http://www.news-medical.net/news/20160314/Could-environmental-toxins-trigger-amyloid-plaques-in-the-brain-An-interview-with-Dr-Paul-Alan-Cox.aspx

Environmental toxin linked to dementia, study shows
https://www.washingtonpost.com/local/social-issues/environmental-toxin-linked-to-dementia-study-shows/2016/01/19/e78b7ac4-bef7-11e5-83d4-42e3bceea902_story.html?utm_term=.907f2b7cabaa

Tangles and Toxins: An interview with Dr Paul Alan Cox
http://www.hurondigitalpathology.com/resource/tangles-toxins-interview-dr-paul-alan-cox/


Mentions vervet monkeys as an animal model for such research.

Does not appear to mention whether l-serine has been tried enough on humans to decide whether it offers humans any help with these conditions.
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Message 81206 - Posted: 21 Feb 2017, 20:33:19 UTC
Last modified: 21 Feb 2017, 20:40:52 UTC

Alzheimer\'s researchers find molecule that delays onset of disease
Guardian.article

Could the Rosetta@Home researchers interested in Alzheimer\'s check whether the 3D structure of the Brichos molecule is ready to use, and if not, add it to the list of molecules for structure investigation?
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Message 81207 - Posted: 21 Feb 2017, 21:12:45 UTC

I just found that Brichos is a family of molecules, not just one.

Some articles that may name the most important type:

(title will not copy and paste)
BCJ article

Molecular inhibitor breaks cycle that leads to Alzheimer’s
Molecular inhibitor breaks cycle that leads to Alzheimer’s

High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C.
High-resolution structure of a BRICHOS domain

BRICHOS Domains Efficiently Delay Fibrillation of Amyloid β-Peptide*
BRICHOS Domains Efficiently Delay Fibrillation of Amyloid β-Peptide

Molecule could protect against Alzheimer\'s disease
Molecule could protect against Alzheimer\'s disease

Brichos protein may prevent brain damage in Alzheimer’s
Brichos protein may prevent brain damage in Alzheimer’s
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Message 88038 - Posted: 9 Jan 2018, 9:59:38 UTC
Last modified: 9 Jan 2018, 9:59:50 UTC

Bad news about Alzheimer and Parkinson

After Merck, now also Pfizer cuts research about Alzheimer
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Profile rochester new york
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Message 88976 - Posted: 23 May 2018, 0:43:16 UTC

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Message boards : Cafe Rosetta : BMAA, Alzheimer\'s, Parkinson\'s, and ALS



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