Dear Rosetta@home Participants,
A wonderful aspect of Rosetta@home for me has been the marvelous
contributions of the many dedicated volunteers around the world.
We are about to begin the 7th biennial CASP Structure Prediction
Experiment and from May 10th until August 1st our need for computing
power will be even greater. In a bid to solicit more of your
'crunching time', R@H volunteers have put together the following letter
which we are sending to all participants. With all of your
collective efforts it should be possible to do wonders! Thank you! David Baker
Dear Rosetta@home Contributors,
We are writing you to thank you for donating your computer time to Rosetta@home.
We'd also like to bring you an update on recent improvements as well as ask for your help
during this year's Critical Assessment of Techniques for Protein
Structure Prediction (CASP7).
is working to develop software to accurately predict the folding
structure of proteins, which is a key function in developing cures for
diseases such as AIDS, cancer, and Alzheimer's. The Rosetta software is
used by other scientists and distributed computing projects. Any
improvement we can make in this project will benefit other scientists
and projects as well.
Cutting-Edge Research with an all new Application package
science application has improved greatly in recent weeks. We now have
"smarter" software and new techniques which help find the best
structures faster. We have also released a number of new features:
- Work unit runtimes based on preference setting can minimize your internet use.
- More frequent saves (checkpointing), means more science output and more credits for you and your team.
- The "Watchdog" keeps work flowing by ending work units that appear stuck or hung.
- All work units will receive credit even if they return late or with an error result.
All these improvements guarantee a problem-free and most useful contribution of your valuable computer time.
CASP7 is here - Be part of the competition and the winning team!
There are many science teams working on protein
studies, and every 2 years they conduct a contest of sorts, to define
the current state-of-the-art. Now the 2006 event is underway, and you
can help. CASP will present proteins no one has ever seen before and ask
the research teams to give their best structure predictions for this
computationally intense problem. We are very hopeful the improved
Rosetta software, now with the added power of distributed computing,
will again find the most accurate predictions.
CASP7 runs from May 10th to August 1st. The more
computing power we apply, the better the predictions become. Please be
sure to run Rosetta@home, at least during the three month period of the
competition. Read more about CASP7, and check for published results on the Rosetta@home website through the end of the year.
Be a part of the project team with new information and user recognition
A number of new informational features have been added to help you participate with the research team:
The project staff is very responsive to
questions and suggestions and is working to incorporate them into
Rosetta application improvements.
What you can do to help
- If you discontinued Rosetta for any reason, please attach again and you will find the application improvements have resolved the problems many were having.
- Dedicate a greater resource share to Rosetta, at least during CASP7.
- Attach additional computers to the project.
- Contact your friends and teammates and help them learn more about Rosetta so they will want to crunch more too. Here is a simple explanation you might use.
- If you are a member of a team, please ask for more Rosetta processing time on your team message boards.
Thank you for your past participation, and we hope you can provide additional support to Rosetta@home in the future.
Mark, Joachim, Gerry and the Rosetta@home volunteers
P.S.: Still not convinced? Take a look at "10 reasons why I support Rosetta@home and you should too."
P.P.S.: Your account preferences suggest that you wouldn't mind recieving our rare newsletters. If this is not true, you can 'opt-out' of future mailings by changing the "Should Rosetta@home send you email newsletters?" setting in your account preferences here: Rosetta@home preferences